Humulin 50/50 and Matzim LA
Determining the interaction of Humulin 50/50 and Matzim LA and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:A single case report suggests that diltiazem may decrease the hypoglycemic effect of insulin. The mechanism of interaction is unknown. Diltiazem 180 mg/day reportedly had no effect on glucose levels in normal subjects. In addition, diltiazem 240 to 360 mg/day had no significant effects on glucose control in 23 hypertensive patients with Type II diabetes. While no special precautions appear to be necessary, patients may consider monitoring blood glucose more closely during the first few days or weeks of diltiazem therapy until glucose control is assured.
- Pershadsingh HA, Grant N, McDonald JM "Association of diltiazem therapy with increased insulin resistance in a patient with type I diabetes mellitus." JAMA 257 (1987): 930-1
Generic Name: insulin isophane / insulin regular
Brand name: Humulin 50/50, Novolin 70/30, Humulin 70/30, HumuLIN 70/30 KwikPen, Novolin 70/30, ReliOn/Novolin 70/30, Humulin 50/50, Insulin Pork Mix, HumuLIN 70/30 Pen, NovoLIN 70/30 Innolet, NovoLIN 70/30 PenFill, Relion NovoLIN 70/30 Innolet, NovoLIN 70/30 FlexPen, ReliOn/NovLIN 70/30 FlexPen
Synonyms: n.a.
Generic Name: diltiazem
Brand name: Cardizem, Cartia XT, Dilacor XR, Dilt-CD, Diltia XT, Diltzac, Matzim LA, Taztia XT, Tiazac, Cardizem CD, Dilt-XR, Tiazac, Cardizem LA, Tiazac Extended Release Capsules
Synonyms: Matzim LA (Oral)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Humulin 50/50-Mavenclad
- Humulin 50/50-Mavik
- Humulin 50/50-Mavyret
- Humulin 50/50-Maxair
- Humulin 50/50-Maxair Autohaler
- Humulin 50/50-Maxalt
- Matzim LA-Humulin 70/30
- Matzim LA-HumuLIN 70/30 KwikPen
- Matzim LA-Humulin L
- Matzim LA-Humulin N
- Matzim LA-Humulin N (Insulin NPH (InnoLets, Pens, and PenFill Cartridges))
- Matzim LA-Humulin N (Insulin NPH (Vials))
Humulin 50/50 - Matzim LA 
Humulin 50/50 - Matzim LA 
Humulin 50/50 - Matzim LA 
Humulin 50/50 - Matzim LA 
Humulin 50/50 - Matzim LA 
Humulin 50/50 - Matzim LA 
Humulin 50/50 - Matzim LA 
Humulin 50/50 - Matzim LA 
Humulin 50/50 - Matzim LA 
Humulin 50/50 - Matzim LA 
Humulin 50/50 - Matzim LA 
Humulin 50/50 - Matzim LA