Hyaluronidase and trastuzumab and Paclitaxel protein-bound Intravenous
Determining the interaction of Hyaluronidase and trastuzumab and Paclitaxel protein-bound Intravenous and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using trastuzumab together with PACLitaxel protein-bound may increase the effects of trastuzumab. Contact your doctor if you experience chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling, swelling, rapid weight gain, cough or wheezing, white patches or sores inside your mouth or on your lips, or fever, chills, body aches, and flu symptoms. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Non-human studies have demonstrated that paclitaxel can significantly increase the serum levels and decrease the clearance of trastuzumab. The mechanism is unknown.
MANAGEMENT: Patients should be monitored closely for signs of trastuzumab toxicity (e.g., cardiotoxicity, bone marrow depression).
- "Product Information. Herceptin (trastuzumab)." Genentech, South San Francisco, CA.
Generic Name: hyaluronidase / trastuzumab
Brand name: Herceptin Hylecta
Synonyms: Trastuzumab and Hyaluronidase
Generic Name: paclitaxel protein-bound
Brand name: Abraxane
Synonyms: Paclitaxel protein-bound, PACLitaxel (Protein Bound)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Hyaluronidase and trastuzumab-Pacnex
- Hyaluronidase and trastuzumab-Pacnex LP
- Hyaluronidase and trastuzumab-Pacnex MX
- Hyaluronidase and trastuzumab-Pain Enz Topical
- Hyaluronidase and trastuzumab-Pain Relief PM Extra Strength
- Hyaluronidase and trastuzumab-Pain Reliever Plus
- Paclitaxel protein-bound Intravenous-Hyaluronidase injection
- Paclitaxel protein-bound Intravenous-Hyaluronidase Injection (Human)
- Paclitaxel protein-bound Intravenous-Hyaluronidase Subcutaneous, Injection
- Paclitaxel protein-bound Intravenous-Hyate:C
- Paclitaxel protein-bound Intravenous-Hybrisil
- Paclitaxel protein-bound Intravenous-Hycamtin