Hycamtin oral/injection and Palifermin
Determining the interaction of Hycamtin oral/injection and Palifermin and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Palifermin is used to treat painful mouth ulcers that can occur from chemotherapy. However, the timing of the dosing of palifermin relative to chemotherapy is important. Palifermin should generally not be used within 24 hours before or after chemotherapy. Otherwise, the mouth ulcers may actually worsen or heal more slowly. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:ADJUST DOSING INTERVAL: In a clinical trial, administration of palifermin within 24 hours of chemotherapy resulted in increased severity and duration of oral mucositis, presumably due to increased sensitivity of the rapidly dividing epithelial cells in the immediate post-chemotherapy period.
MANAGEMENT: Palifermin should not be administered within 24 hours before, during infusion of, or within 24 hours after administration of myelotoxic chemotherapy.
- "Product Information. Kepivance (palifermin)." Shire US Inc, Florence, KY.
Generic Name: topotecan
Brand name: Hycamtin
Synonyms: Hycamtin (oral/injection), Hycamtin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Hycamtin oral/injection-Palifermin Intravenous
- Hycamtin oral/injection-Paliperidone
- Hycamtin oral/injection-Paliperidone Extended-Release Tablets
- Hycamtin oral/injection-Paliperidone injection
- Hycamtin oral/injection-Paliperidone Intramuscular
- Hycamtin oral/injection-Palladone
- Palifermin-Hycet
- Palifermin-Hycodan
- Palifermin-Hycodan Oral
- Palifermin-Hycodan Oral Solution
- Palifermin-Hycofenix
- Palifermin-Hycomine