About us Contacts Drug interactions: 390 212
Drug search by name

Hydralazine and Pepto-Bismol (Bismuth Subsalicylate Chewable Tablets)

Determining the interaction of Hydralazine and Pepto-Bismol (Bismuth Subsalicylate Chewable Tablets) and the possibility of their joint administration.

Check result:
Hydralazine <> Pepto-Bismol (Bismuth Subsalicylate Chewable Tablets)
Relevance: 07.09.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Before taking hydrALAZINE, tell your doctor if you also use bismuth subsalicylate. This combination may cause dizziness, headaches, or blurred vision. If you take both medications together, tell your doctor if you have any of these symptoms. You may need a dose adjustment or need your blood pressure checked more often. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Nonsteroidal anti-inflammatory drugs (NSAIDs) may attenuate the antihypertensive effect of hydralazine and dihydralazine. This interaction suggests that prostaglandins play a pivotal role in the vasodilatory effects of hydralazine. However, data have been conflicting.

MANAGEMENT: Recommended management consists of monitoring the antihypertensive effectiveness of hydralazine or dihydralazine during therapy, increasing the dosage as necessary, or decreasing or substituting another drug for the NSAID.

References
  • Cinquegrani MP, Liang CS "Indomethacin attenuates the hypotensive action of hydralazine." Clin Pharmacol Ther 39 (1986): 564-70
Hydralazine

Generic Name: hydralazine

Brand name: Apresoline

Synonyms: HydrALAZINE

Pepto-Bismol (Bismuth Subsalicylate Chewable Tablets)

Generic Name: bismuth subsalicylate

Brand name: Bismarex, Bismatrol, Bismatrol Maximum Strength, Kaopectate, Kola-Pectin DS, Maalox Total Stomach Relief, Peptic Relief, Pepto-Bismol, Pink Bismuth, Pepto-Bismol Maximum Strength, Maximum Strength Stress, Stress Maximum Strength, Kaopectate Extra Strength, Childrens Kaopectate, Kapectolin, Kao-Tin Bismuth Subsalicylate Formula, Kaopectate Anti-Diarrheal Upset Stomach Reliever, K-Pek, Soothe Chewable, Soothe Regular Strength, Soothe Maximum Strength, Soothe Caplets, Percy Medicine, Pepto-Bismol InstaCool

Synonyms: Pepto-Bismol

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.