Hydralazine and isosorbide dinitrate and Omeprazole Delayed-Release Capsules
Determining the interaction of Hydralazine and isosorbide dinitrate and Omeprazole Delayed-Release Capsules and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Omeprazole may inhibit the drug delivery of oral nitrates. Antianginal effects may be diminished, and myocardial ischemia may be exacerbated. If an interaction is suspected, alternate acid-suppressant therapy may be considered.
- Kajinami K, Mabuchi H "Omeprazole and diminished antianginal drug delivery." Ann Intern Med 121 (1994): 385-6
Generic Name: hydralazine / isosorbide dinitrate
Brand name: BiDil
Synonyms: Isosorbide Dinitrate and Hydralazine
Generic Name: omeprazole
Brand name: FIRST Omeprazole, Omeprazole + SyrSpend SF Alka, Prilosec, Prilosec OTC, Zegerid>, Prilosec, Prilosec OTC
Synonyms: Omeprazole
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Hydralazine and isosorbide dinitrate-Omeprazole Delayed-Release Capsules and Tablets (OTC)
- Hydralazine and isosorbide dinitrate-Omeprazole Orally-Disintegrating Tablets
- Hydralazine and isosorbide dinitrate-Omeprazole Powder for Oral Suspension
- Hydralazine and isosorbide dinitrate-Omeprazole Tablets
- Hydralazine and isosorbide dinitrate-Omeprazole, Clarithromycin, and Amoxicillin
- Hydralazine and isosorbide dinitrate-Omidria
- Omeprazole Delayed-Release Capsules-Hydralazine Hydrochloride
- Omeprazole Delayed-Release Capsules-Hydralazine Injection
- Omeprazole Delayed-Release Capsules-Hydralazine Oral, Injection, Intravenous
- Omeprazole Delayed-Release Capsules-Hydralazine Tablets
- Omeprazole Delayed-Release Capsules-Hydrea
- Omeprazole Delayed-Release Capsules-Hydrisalic Topical