Hydrochlorothiazide and aliskiren and Rifampin
Determining the interaction of Hydrochlorothiazide and aliskiren and Rifampin and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Animal studies have suggested that coadministration with inducers of P-glycoprotein transport may decrease the bioavailability of aliskiren. The clinical significance is unknown.
- EMEA. European Medicines Agency "EPARs. European Union Public Assessment Reports. Available from: URL: http://www.ema.europa.eu/ema/index.jsp?curl=pages/includes/medicines/medicines_landingpage.jsp&mid."
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: aliskiren / hydrochlorothiazide
Brand name: Tekturna HCT
Synonyms: Aliskiren and Hydrochlorothiazide
Generic Name: rifampin
Brand name: Rifadin, Rifadin IV, Rimactane
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Hydrochlorothiazide and aliskiren-Rifampin and Isoniazid
- Hydrochlorothiazide and aliskiren-Rifampin Capsules
- Hydrochlorothiazide and aliskiren-Rifampin Injection
- Hydrochlorothiazide and aliskiren-Rifampin Intravenous
- Hydrochlorothiazide and aliskiren-Rifampin Oral, Intravenous
- Hydrochlorothiazide and aliskiren-Rifampin, Isoniazid, and Pyrazinamide
- Rifampin-Hydrochlorothiazide and amiloride
- Rifampin-Hydrochlorothiazide and benazepril
- Rifampin-Hydrochlorothiazide and bisoprolol
- Rifampin-Hydrochlorothiazide and candesartan
- Rifampin-Hydrochlorothiazide and captopril
- Rifampin-Hydrochlorothiazide and enalapril