Hydrochlorothiazide and amiloride and Irinotecan Intravenous
Determining the interaction of Hydrochlorothiazide and amiloride and Irinotecan Intravenous and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using irinotecan together with aMILoride may increase the risk of dehydration and electrolyte abnormalities. Irinotecan can cause severe vomiting and diarrhea, which leads to water and electrolyte loss from the body that may be worsened with the use of a diuretic. Talk to your doctor if you have any questions or concerns. You should seek prompt medical attention if you experience vomiting or diarrhea that is not responsive to medications. In severe cases, dehydration and electrolyte abnormalities can lead to irregular heart rhythm, seizures, and kidney problems. Contact your doctor if you experience potential signs and symptoms of fluid and electrolyte depletion such as dizziness, lightheadedness, dry mouth, thirst, fatigue, weakness, muscle cramps, decreased urination, palpitation, and increased heart rate. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: Irinotecan-induced vomiting or diarrhea may increase the risk and/or severity of dehydration produced by diuretics.
MANAGEMENT: Concomitant use of diuretics during irinotecan administration or during periods of vomiting or diarrhea that may follow is not recommended.
- "Product Information. Camptosar (irinotecan)." Pharmacia and Upjohn, Kalamazoo, MI.
Generic Name: amiloride / hydrochlorothiazide
Brand name: Moduretic 5-50
Synonyms: Amiloride and Hydrochlorothiazide
Generic Name: irinotecan
Brand name: Camptosar
Synonyms: Irinotecan, Irinotecan (Conventional)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Hydrochlorothiazide and amiloride-Irinotecan liposomal
- Hydrochlorothiazide and amiloride-Irinotecan liposome Intravenous
- Hydrochlorothiazide and amiloride-Iron 100/C
- Hydrochlorothiazide and amiloride-Iron 21/7
- Hydrochlorothiazide and amiloride-Iron and Docusate
- Hydrochlorothiazide and amiloride-Iron and Folic Acid
- Irinotecan Intravenous-Hydrochlorothiazide and benazepril
- Irinotecan Intravenous-Hydrochlorothiazide and bisoprolol
- Irinotecan Intravenous-Hydrochlorothiazide and candesartan
- Irinotecan Intravenous-Hydrochlorothiazide and captopril
- Irinotecan Intravenous-Hydrochlorothiazide and enalapril
- Irinotecan Intravenous-Hydrochlorothiazide and fosinopril