Hydrochlorothiazide and candesartan and Propulsid (Cisapride Tablets)
Determining the interaction of Hydrochlorothiazide and candesartan and Propulsid (Cisapride Tablets) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using cisapride together with hydroCHLOROthiazide is not recommended. Combining these medications can increase the risk of an irregular heart rhythm that may be serious. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats during treatment with cisapride. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. **Cisapride (Propulsid) is no longer marketed in the United States. You should only be taking cisapride if you are obtaining the medication from your doctor though a Limited Access Program developed jointly by the manufacturer and the FDA.**
Professional:CONTRAINDICATED: Some diuretics may produce hypokalemia and hypomagnesemia which could potentiate the risk of cisapride-induced arrhythmias in patients receiving both drugs concomitantly. Prolonged QT interval, torsades de pointes, and death have been reported.
MANAGEMENT: Cisapride is contraindicated in patients with uncorrected hypokalemia and hypomagnesemia, such as those taking potassium-wasting diuretics.
- "Product Information. Propulsid (cisapride)." Janssen Pharmaceutica, Titusville, NJ.
Generic Name: candesartan / hydrochlorothiazide
Brand name: Atacand HCT
Synonyms: Candesartan and Hydrochlorothiazide
Generic Name: cisapride
Brand name: Propulsid
Synonyms: Propulsid (Suspension), Propulsid
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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