Hydrochlorothiazide and captopril and Panobinostat Lactate

• Generic Name: captopril / hydrochlorothiazide
• Dosage Forms: n.a.
• Other Brand Names: Capozide 25/15, Capozide 25/25, Capozide 50/15, Capozide 50/25

Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Captopril is in a group of drugs called ACE inhibitors. ACE stands for angiotensin converting enzyme. Captopril lowers blood pressure and also relieves symptoms of fluid retention.

Hydrochlorothiazide and captopril is a combination medicine used to treat hypertension (high blood pressure).

Hydrochlorothiazide and captopril may also be used for purposes not listed in this medication guide.

• Generic Name: panobinostat
• Dosage Forms: n.a.
• Other Brand Names: Farydak

In combination with bortezomib and dexamethasone for treatment of multiple myeloma in patients who have received ≥2 prior therapies, including bortezomib and an immunomodulatory agent (designated an orphan drug by FDA for use in this condition ).

Accelerated approval based on progression-free survival; continued approval may be contingent on verification and description of clinical benefit in confirmatory studies.