Hydrochlorothiazide and irbesartan and Pemetrexed Disodium

• Generic Name: hydrochlorothiazide / irbesartan
• Dosage Forms: n.a.
• Other Brand Names: Avalide

Hydrochlorothiazide and irbesartan is a combination medicine used to treat high blood pressure (hypertension).

Hydrochlorothiazide and irbesartan contains a diuretic (water pill) and an angiotensin II receptor blocker (ARB).

Hydrochlorothiazide and irbesartan may also be used for purposes not listed in this medication guide.

• Generic Name: pemetrexed
• Dosage Forms: n.a.
• Other Brand Names: Alimta

Used in combination with cisplatin for the treatment of malignant pleural mesothelioma in adults whose disease is unresectable or who otherwise are not candidates for potentially curative surgery (designated an orphan drug by FDA for this indication).

Monotherapy for the treatment of locally advanced or metastatic non-small cell lung cancer in adults who have received prior chemotherapy. Efficacy based on surrogate end points of tumor response rate; improvement in disease-related symptoms or increased survival not demonstrated in clinical studies.