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Hydrochlorothiazide and methyldopa and Namenda

Determining the interaction of Hydrochlorothiazide and methyldopa and Namenda and the possibility of their joint administration.

Check result:

Hydrochlorothiazide and methyldopa <> Namenda

Relevance: 16.11.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Theoretically, the concomitant administration of memantine and other drugs that undergo active renal tubular secretion may result in altered plasma levels of both drugs. The clinical significance is unknown. When hydrochlorothiazide/triamterene and memantine were coadministered in a clinical study, the bioavailability of hydrochlorothiazide decreased by 20% and there was no change in memantine or triamterene bioavailability.

References

"Product Information. Namenda (memantine)." Forest Pharmaceuticals, St. Louis, MO.

Hydrochlorothiazide and methyldopa

Generic Name: hydrochlorothiazide / methyldopa

Brand name: Aldoril 15, Aldoril 25, Aldoril D30, Aldoril D50

Synonyms: Methyldopa and Hydrochlorothiazide

What is Hydrochlorothiazide and methyldopa?

Namenda

Generic Name: memantine

Brand name: Namenda, Namenda XR

Synonyms: n.a.

What is Namenda?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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