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Hydrochlorothiazide and quinapril and Monodox

Determining the interaction of Hydrochlorothiazide and quinapril and Monodox and the possibility of their joint administration.

Check result:

Hydrochlorothiazide and quinapril <> Monodox

Relevance: 15.05.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using doxycycline together with quinapril may cause doxycycline to be less effective. To avoid this problem, you should try to separate the doses of doxycycline and quinapril by two to four hours. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADJUST DOSING INTERVAL: Administration of a tetracycline with quinapril may significantly decrease tetracycline serum concentrations. The proposed mechanism is chelation of tetracycline by the magnesium excipient in quinapril. Coadministration reduced tetracycline absorption by 28% to 37%.

MANAGEMENT: The manufacturer does not make a specific recommendation, but generally the administration of tetracyclines and magnesium-containing products should be separated by two to four hours.

References

Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
"Product Information. Seysara (sarecycline)." Allergan Inc, Irvine, CA.
"Product Information. Nuzyra (omadacycline)." Paratek Pharmaceuticals, Inc., Boston, MA.

Hydrochlorothiazide and quinapril

Generic Name: hydrochlorothiazide / quinapril

Brand name: Accuretic, Quinaretic

Synonyms: Quinapril and Hydrochlorothiazide

What is Hydrochlorothiazide and quinapril?

Monodox

Generic Name: doxycycline

Brand name: Acticlate, Adox Pak 2/100, Adoxa, Adoxa Pak 1/100, Adoxa Pak 1/150, Avidoxy, Monodox, Morgidox, Oraxyl, TargaDOX, Vibramycin, Adoxa CK, Adoxa Pak, Adoxa TT, Alodox, Avidoxy, Doryx, Mondoxyne NL, Oracea, Periostat Targadox, Vibramycin Calcium, Vibramycin Hyclate, Vibramycin monohydrate, Vibra-Tabs, Doxy 100, TargaDOX

Synonyms: n.a.

What is Monodox?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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