Hydrochlorothiazide Capsules and Ipilimumab Intravenous

• Generic Name: hydrochlorothiazide
• Dosage Forms: capsule
• Other Brand Names: Aquazide H, HydroDIURIL, Microzide,

HCTZ (hydrochlorothiazide) is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

HCTZ treats fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or kidney disorders, or edema caused by taking steroids or estrogen. This medication is also used to treat high blood pressure (hypertension).

HCTZ may also be used for purposes not listed in this medication guide.

• Generic Name: ipilimumab
• Dosage Forms: n.a.
• Other Brand Names: Yervoy

Ipilimumab injection is used to treat melanoma (a type of skin cancer) that has spread or cannot be removed by surgery. It is a monoclonal antibody that changes the immune system to help control the growth of cancer cells in the skin.

Ipilimumab injection is also used to help prevent melanoma from coming back after surgical removal.

Ipilimumab injection is also used in combination with other medicines (eg, nivolumab) to treat patients with previously untreated kidney cancer that has spread throughout the body.

Ipilimumab injection is also used with nivolumab to treat microsatellite instability high (MSI-H) or mismatch repair deficient (dMMR) colorectal cancer (cancer of the colon or rectum) that has spread. It is given to patients who have received other cancer treatments (eg, fluoropyrimidine, oxaliplatin, irinotecan) but did not work well.

Ipilimumab is to be given only by or under the immediate supervision of your doctor.