Hydrocodone and ibuprofen and Naloxone Hydrochloride
Determining the interaction of Hydrocodone and ibuprofen and Naloxone Hydrochloride and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:The following interaction applies only if you are using naloxone in an injectable formulation: naloxone can reverse the effects of HYDROcodone. If you are a physically dependent patient you may experience withdrawal symptoms. This can cause nausea, vomiting, diarrhea, aches, fever, runny nose, sneezing, nervousness, irritability, shivering, and abdominal cramps. Talk to your doctor if you have any questions or concerns. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: This warning does not apply to the naloxone component in non-injectable formulations of naloxone-containing combination medicines. Naloxone injection is an antagonist that will reverse the actions of opiates. This reversal can occur when the opiate drug is being used clinically and when it is being abused. Physically dependent patients may experience withdrawal symptoms. Abrupt postoperative opioid reversal has resulted in hypotension, ventricular tachycardia and fibrillation, pulmonary edema, cardiac arrest, encephalopathy, and death.
MANAGEMENT: Patients receiving naloxone injection should be monitored for changes in vital signs, nausea, vomiting, diarrhea, aches, fever, runny nose, sneezing, nervousness, irritability, shivering, abdominal cramps.
- Cerner Multum, Inc. "Australian Product Information." O 0
- Gilman AG, Rall TW, Nies AS, Taylor P, eds. "Goodman and Gilman's the Pharmacological Basis of Therapeutics. 8th ed." New York, NY: Pergamon Press Inc. (1990):
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Narcan (naloxone)." DuPont Pharmaceuticals, Wilmington, DE.
Generic Name: hydrocodone / ibuprofen
Brand name: Ibudone, Vicoprofen, Reprexain, Xylon 10, Xylon
Synonyms: Hydrocodone and Ibuprofen
Generic Name: naloxone
Brand name: Narcan, Evzio
Synonyms: Naloxone (nasal), Naloxone
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Hydrocodone and ibuprofen-Naloxone Injection
- Hydrocodone and ibuprofen-Naloxone nasal
- Hydrocodone and ibuprofen-Naloxone Nasal Spray
- Hydrocodone and ibuprofen-Naltrexone
- Hydrocodone and ibuprofen-Naltrexone and Bupropion
- Hydrocodone and ibuprofen-Naltrexone Hydrochloride And Bupropion Hydrochloride
- Naloxone Hydrochloride-Hydrocodone and Pseudoephedrine
- Naloxone Hydrochloride-Hydrocodone Bitartrate
- Naloxone Hydrochloride-Hydrocodone Bitartrate and Acetaminophen Oral Solution
- Naloxone Hydrochloride-Hydrocodone Extended-Release Capsules
- Naloxone Hydrochloride-Hydrocodone Extended-Release Tablets
- Naloxone Hydrochloride-Hydrocodone Polistirex and Chlorpheniramine Polistirex Suspension