Hydrocodone and ibuprofen and Zidovudine Capsules and Tablets
Determining the interaction of Hydrocodone and ibuprofen and Zidovudine Capsules and Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using zidovudine together with ibuprofen may increase the risk of bleeding in HIV-positive patients with hemophilia. However, the interaction is not fully understood, and evidence is limited. Talk to your doctor or pharmacist if you have any concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Limited clinical data suggest that the concomitant use of zidovudine with nonsteroidal anti-inflammatory agents may increase the risk of hematological toxicity and/or bleeding in HIV-positive patients with hemophilia. The mechanism is unknown.
MANAGEMENT: It is recommended to monitor patients for side effects and bleeding during concomitant use.
- Cerner Multum, Inc. "Australian Product Information." O 0
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
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- Sahai J, Gallicano K, Conway B, et al. "Lack of pharmacokinetic interaction between naproxen (N) and zidovudine (Z)." Clin Pharmacol Ther 51 (1992): 184
- Sahai J, Gallicano K, Garber G, et al. "Evaluation of the in vivo effect of naproxen on zidovudine pharmacokinetics in patients infected with human immunodeficiency virus." Clin Pharmacol Ther 52 (1992): 464-70
- Burger DM, Meenhorst PL, Koks CH, Beijnen JH "Drug interactions with zidovudine." AIDS 7 (1993): 445-60
Generic Name: hydrocodone / ibuprofen
Brand name: Ibudone, Vicoprofen, Reprexain, Xylon 10, Xylon
Synonyms: Hydrocodone and Ibuprofen
Generic Name: zidovudine
Brand name: Retrovir
Synonyms: Zidovudine (oral/injection), Zidovudine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Hydrocodone and ibuprofen-Zidovudine Injection
- Hydrocodone and ibuprofen-Zidovudine Intravenous
- Hydrocodone and ibuprofen-Zidovudine Oral Solution
- Hydrocodone and ibuprofen-Zidovudine oral/injection
- Hydrocodone and ibuprofen-Zidovudine Syrup
- Hydrocodone and ibuprofen-Zidovudine Tablets
- Zidovudine Capsules and Tablets-Hydrocodone and Pseudoephedrine
- Zidovudine Capsules and Tablets-Hydrocodone Bitartrate
- Zidovudine Capsules and Tablets-Hydrocodone Bitartrate and Acetaminophen Oral Solution
- Zidovudine Capsules and Tablets-Hydrocodone Extended-Release Capsules
- Zidovudine Capsules and Tablets-Hydrocodone Extended-Release Tablets
- Zidovudine Capsules and Tablets-Hydrocodone Polistirex and Chlorpheniramine Polistirex Suspension