Hydrocodone Bitartrate and Acetaminophen Oral Solution and Zantac (Ranitidine Syrup)
Determining the interaction of Hydrocodone Bitartrate and Acetaminophen Oral Solution and Zantac (Ranitidine Syrup) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Animal studies have suggested that ranitidine may potentiate the hepatotoxicity of acetaminophen, however, a double-blind placebo-controlled crossover study has failed to confirm this finding in humans. Acetaminophen dosage adjustments are not indicated.
- Rogers SA, Gale KC, Newton JF, et al "Inhibition by ranitidine of acetaminophen conjugation and its possible role in ranitidine potentiation of acetaminophen-induced hepatotoxicity." J Pharmacol Exp Ther 245 (1988): 887-94
- Jack D, Thomas M, Skidmore IF "Ranitidine and paracetamol metabolism." Lancet 2 (1985): 1067
Generic Name: acetaminophen / hydrocodone
Brand name: Anexsia, Dolorex Forte, Hycet, Liquicet, Lorcet, Lortab, Maxidone, Norco, Polygesic, Stagesic, Vicodin, Xodol, Zamicet, Zydone, Verdrocet, Lortab 10/325, Lortab 5/325, Lortab 75/325, Lortab Elixir, Zyfrel
Synonyms: Acetaminophen and Hydrocodone, Hydrocodone and Acetaminophen
Generic Name: ranitidine
Brand name: Zantac
Synonyms: Zantac
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Hydrocodone Bitartrate and Acetaminophen Oral Solution-Zantac (Ranitidine Tablets and Capsules)
- Hydrocodone Bitartrate and Acetaminophen Oral Solution-Zantac Cool Mint
- Hydrocodone Bitartrate and Acetaminophen Oral Solution-Zantac Injection
- Hydrocodone Bitartrate and Acetaminophen Oral Solution-Zapzyt Cleansing Topical
- Hydrocodone Bitartrate and Acetaminophen Oral Solution-Zapzyt Topical
- Hydrocodone Bitartrate and Acetaminophen Oral Solution-Zarah
- Zantac (Ranitidine Syrup)-Hydrocodone Extended-Release Capsules
- Zantac (Ranitidine Syrup)-Hydrocodone Extended-Release Tablets
- Zantac (Ranitidine Syrup)-Hydrocodone Polistirex and Chlorpheniramine Polistirex Suspension
- Zantac (Ranitidine Syrup)-Hydrocodone, Chlorpheniramine, and Pseudoephedrine
- Zantac (Ranitidine Syrup)-Hydrocodone, Pseudoephedrine, and Guaifenesin
- Zantac (Ranitidine Syrup)-Hydrocortisone