Hydrocortisone Acetate, Pramoxine Rectal Cream, and Diosmiplex Tablets and Tacrolimus Intravenous

• Generic Name: diosmiplex / hydrocortisone / pramoxine topical
• Dosage Forms: n.a.
• Other Brand Names: Analpram Advanced

• It is used to treat signs of hemorrhoids or rectal irritation.

• Generic Name: tacrolimus
• Dosage Forms: n.a.
• Other Brand Names: Astagraf XL, Envarsus XR, Prograf, Hecoria

Tacrolimus injection is used together with other medicines to prevent the body from rejecting a transplanted organ (eg, kidney, liver, or heart). Tacrolimus may be used with steroids, azathioprine, or mycophenolate mofetil. Tacrolimus belongs to a group of medicines known as immunosuppressive agents.

When a patient receives an organ transplant, the body's white blood cells will try to get rid of (reject) the transplanted organ. Tacrolimus works by suppressing the immune system to prevent the white blood cells from trying to get rid of the transplanted organ.

Tacrolimus is a very strong medicine. It can cause side effects that can be very serious, such as kidney problems. It may also decrease the body's ability to fight infections. You and your doctor should talk about the benefits of tacrolimus as well as the risks of using it.

Tacrolimus is to be given only by or under the direct supervision of a doctor.