Hydrocortisone Injection Solution and Indacaterol and glycopyrrolate Inhalation
Determining the interaction of Hydrocortisone Injection Solution and Indacaterol and glycopyrrolate Inhalation and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Although they are often combined in clinical practice, the concomitant use of beta-2 adrenergic agonists and corticosteroids may result in additive hypokalemic effects. Since beta-2 agonists can sometimes cause QT interval prolongation, the development of hypokalemia may potentiate the risk of ventricular arrhythmias including torsade de pointes. However, clinical data are limited, and the potential significance is unknown. Patients who are receiving systemic or nebulized formulations of beta-2 agonists, high dosages of inhaled beta-2 agonists, or systemic corticosteroid therapy may be at a greater risk of developing hypokalemia.
- "Product Information. Foradil (formoterol)" Novartis Pharmaceuticals, East Hanover, NJ.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- Cerner Multum, Inc. "Australian Product Information." O 0
- Agencia EspaƱola de Medicamentos y Productos Sanitarios Healthcare "Centro de informaciĆ³n online de medicamentos de la AEMPS - CIMA. Available from: URL: https://cima.aemps.es/cima/publico/home.html." ([2018]):
Generic Name: hydrocortisone
Brand name: Cortef, Colocort, Cortenema, Cortifoam, Solu-Cortef
Synonyms: Hydrocortisone, Hydrocortisone (Systemic)
Generic Name: glycopyrrolate / indacaterol
Brand name: Utibron Neohaler
Synonyms: Glycopyrrolate and indacaterol (inhalation), Indacaterol and Glycopyrrolate
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Hydrocortisone Injection Solution-Indacaterol inhalation
- Hydrocortisone Injection Solution-Indacaterol Maleate
- Hydrocortisone Injection Solution-Indapamide
- Hydrocortisone Injection Solution-Inderal
- Hydrocortisone Injection Solution-Inderal Intravenous
- Hydrocortisone Injection Solution-Inderal LA
- Indacaterol and glycopyrrolate Inhalation-Hydrocortisone Iodoquinol Cream
- Indacaterol and glycopyrrolate Inhalation-Hydrocortisone Lotion
- Indacaterol and glycopyrrolate Inhalation-Hydrocortisone Lotion and Protective Emollient Cream
- Indacaterol and glycopyrrolate Inhalation-Hydrocortisone Ointment
- Indacaterol and glycopyrrolate Inhalation-Hydrocortisone probutate Topical application
- Indacaterol and glycopyrrolate Inhalation-Hydrocortisone Rectal Cream