Hydrocortisone Rectal Suspension and Indacaterol and Glycopyrrolate
Determining the interaction of Hydrocortisone Rectal Suspension and Indacaterol and Glycopyrrolate and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Although they are often combined in clinical practice, the concomitant use of beta-2 adrenergic agonists and corticosteroids may result in additive hypokalemic effects. Since beta-2 agonists can sometimes cause QT interval prolongation, the development of hypokalemia may potentiate the risk of ventricular arrhythmias including torsade de pointes. However, clinical data are limited, and the potential significance is unknown. Patients who are receiving systemic or nebulized formulations of beta-2 agonists, high dosages of inhaled beta-2 agonists, or systemic corticosteroid therapy may be at a greater risk of developing hypokalemia.
- "Product Information. Foradil (formoterol)" Novartis Pharmaceuticals, East Hanover, NJ.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- Cerner Multum, Inc. "Australian Product Information." O 0
- Agencia EspaƱola de Medicamentos y Productos Sanitarios Healthcare "Centro de informaciĆ³n online de medicamentos de la AEMPS - CIMA. Available from: URL: https://cima.aemps.es/cima/publico/home.html." ([2018]):
Generic Name: hydrocortisone
Brand name: Cortef, Colocort, Cortenema, Cortifoam, Solu-Cortef
Synonyms: Hydrocortisone, Hydrocortisone (Systemic)
Generic Name: glycopyrrolate / indacaterol
Brand name: Utibron Neohaler
Synonyms: Glycopyrrolate and indacaterol (inhalation)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Hydrocortisone Rectal Suspension-Indacaterol and glycopyrrolate Inhalation
- Hydrocortisone Rectal Suspension-Indacaterol inhalation
- Hydrocortisone Rectal Suspension-Indacaterol Maleate
- Hydrocortisone Rectal Suspension-Indapamide
- Hydrocortisone Rectal Suspension-Inderal
- Hydrocortisone Rectal Suspension-Inderal Intravenous
- Indacaterol and Glycopyrrolate-Hydrocortisone Sodium Phosphate
- Indacaterol and Glycopyrrolate-Hydrocortisone Sodium Succinate
- Indacaterol and Glycopyrrolate-Hydrocortisone Suppository
- Indacaterol and Glycopyrrolate-Hydrocortisone Tablets
- Indacaterol and Glycopyrrolate-Hydrocortisone topical
- Indacaterol and Glycopyrrolate-Hydrocortisone Topical application