Hydroxocobalamin Intravenous and Lorbrena

• Generic Name: hydroxocobalamin
• Dosage Forms: n.a.
• Other Brand Names: Cyanokit, Hydroxy-Cobal, Hydro-Cobex, Cobalin-H, Neo-Cytamen, Hydroxocobalamin

Hydroxocobalamin injection is an emergency treatment (antidote) used in patients with known or suspected cyanide poisoning. Cyanide poisoning is a life-threatening condition that requires immediate medical attention. It is more likely to occur if you breathe smoke from closed-space household and industrial fires, or you have swallowed or breathe cyanide (a chemical poison), or your skin is exposed to cyanide. Signs and symptoms include chest tightness, confusion, dilated or enlarged pupils, nausea or vomiting, rapid or shallow breathing, trouble breathing, or seizures.

Hydroxocobalamin is to be given only by or under the direct supervision of a doctor.

• Generic Name: lorlatinib
• Dosage Forms: tablet, film coated
• Other Brand Names: Lorbrena

Lorbrena (lorlatinib) is prescription medicine used to treat a certain type of non-small cell lung cancer that has spread to other parts of the body.

Lorbrena is used only if your cancer has a specific genetic marker (an abnormal "ALK" gene). Your doctor will test you for this gene.

Lorbrena is given after other cancer treatments did not work or have stopped working.

Lorbrena was approved by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, some people responded to this medicine, but further studies are needed.