Hydroxychloroquine Sulfate and Otrexup
Determining the interaction of Hydroxychloroquine Sulfate and Otrexup and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:A small, single dose pharmacokinetic study has indicated that coadministration of methotrexate and chloroquine may lead to a reduced bioavailability of methotrexate. Clinical evidence of this effect has not been established. Consider monitoring the patient more closely for reduced efficacy and adjust the dose of methotrexate if needed.
- Seideman P, Albertioni F, Beck O, Eksborg S, Peterson C "Chloroquine reduces the bioavailability of methotrexate in patients with rheumatoid arthritis - a possible mechanism of reduced hepatotoxicity." Arthritis Rheum 37 (1994): 830-3
Generic Name: hydroxychloroquine
Brand name: Plaquenil, Quineprox
Synonyms: Hydroxychloroquine
Generic Name: methotrexate
Brand name: Methotrexate Sodium, Preservative Free, Otrexup, Rasuvo, Rheumatrex Dose Pack, Trexall, Xatmep
Synonyms: Otrexup (injection)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Hydroxychloroquine Sulfate-Otrexup injection
- Hydroxychloroquine Sulfate-Outgro
- Hydroxychloroquine Sulfate-Ovcon 35
- Hydroxychloroquine Sulfate-Ovidrel
- Hydroxychloroquine Sulfate-Ovidrel injectable
- Hydroxychloroquine Sulfate-Ovidrel Injection
- Otrexup-Hydroxychloroquine Tablets
- Otrexup-Hydroxyprogesterone Caproate
- Otrexup-Hydroxyprogesterone Caproate Injection
- Otrexup-Hydroxyprogesterone Caproate Injection (Makena)
- Otrexup-Hydroxyprogesterone injection
- Otrexup-Hydroxyprogesterone Intramuscular