Hydroxyprogesterone Caproate and Pancreatin

• Generic Name: hydroxyprogesterone
• Dosage Forms: n.a.
• Other Brand Names: Makena, Makena Auto-Injector, Hylutin, Delta-Lutin, Duralutin, Hyprogesterone, Prodrox

Reduction of risk of preterm birth in women with a singleton pregnancy having a history of singleton spontaneous preterm birth (designated an orphan drug by FDA for this use).

Efficacy determined based on improvement in proportion of women who delivered at <37 weeks of gestation; direct clinical benefit (e.g., improvement in neonatal morbidity and mortality) not established.

Safety and efficacy demonstrated only in women with a prior spontaneous singleton birth; not intended for use in women with multiple gestations or other risk factors for preterm birth.

ACOG recommends offering progesterone supplementation for prevention of recurrent preterm birth to women with a singleton pregnancy and a prior spontaneous preterm birth at <37 weeks of gestation due to spontaneous preterm labor or premature rupture of membranes.

• Generic Name: pancreatin
• Dosage Forms: n.a.
• Other Brand Names: Hi-Vegi-Lip, Pancreatin 4X, Donnazyme, Digipepsin, Pan-2400

Pancreatin is a combination of digestive enzymes (proteins). These enzymes are normally produced by the pancreas and are important for digesting fats, proteins, and sugars.

Pancreatin is used to replace digestive enzymes when the body does not have enough of its own. Certain medical conditions can cause this lack of enzymes, such as cystic fibrosis, pancreatitis, pancreatic cancer, or pancreas surgery.

Pancreatin may also be used to treat a condition called steatorrhea (loose, fatty stools).

Pancreatin may also be used for purposes not listed in this medication guide.