Hydroxyprogesterone Caproate and Ticagrelor

• Generic Name: hydroxyprogesterone
• Dosage Forms: n.a.
• Other Brand Names: Makena, Makena Auto-Injector, Hylutin, Delta-Lutin, Duralutin, Hyprogesterone, Prodrox

Reduction of risk of preterm birth in women with a singleton pregnancy having a history of singleton spontaneous preterm birth (designated an orphan drug by FDA for this use).

Efficacy determined based on improvement in proportion of women who delivered at <37 weeks of gestation; direct clinical benefit (e.g., improvement in neonatal morbidity and mortality) not established.

Safety and efficacy demonstrated only in women with a prior spontaneous singleton birth; not intended for use in women with multiple gestations or other risk factors for preterm birth.

ACOG recommends offering progesterone supplementation for prevention of recurrent preterm birth to women with a singleton pregnancy and a prior spontaneous preterm birth at <37 weeks of gestation due to spontaneous preterm labor or premature rupture of membranes.

• Generic Name: ticagrelor
• Dosage Forms: n.a.
• Other Brand Names: Brilinta

Ticagrelor prevents platelets in your blood from sticking together to form an unwanted blood clot that could block an artery.

Ticagrelor is used together with aspirin to lower your risk of having a stroke or serious heart problems after you've had a heart attack or severe chest pain (angina).

Ticagrelor may also be used for purposes not listed in this medication guide.