Hydroxyprogesterone Caproate and Zyloprim

• Generic Name: hydroxyprogesterone
• Dosage Forms: n.a.
• Other Brand Names: Makena, Makena Auto-Injector, Hylutin, Delta-Lutin, Duralutin, Hyprogesterone, Prodrox

Reduction of risk of preterm birth in women with a singleton pregnancy having a history of singleton spontaneous preterm birth (designated an orphan drug by FDA for this use).

Efficacy determined based on improvement in proportion of women who delivered at <37 weeks of gestation; direct clinical benefit (e.g., improvement in neonatal morbidity and mortality) not established.

Safety and efficacy demonstrated only in women with a prior spontaneous singleton birth; not intended for use in women with multiple gestations or other risk factors for preterm birth.

ACOG recommends offering progesterone supplementation for prevention of recurrent preterm birth to women with a singleton pregnancy and a prior spontaneous preterm birth at <37 weeks of gestation due to spontaneous preterm labor or premature rupture of membranes.

• Generic Name: allopurinol
• Dosage Forms: tablet
• Other Brand Names: Zyloprim, Lopurin, Aloprim

Zyloprim reduces the production of uric acid in your body. Uric acid buildup can lead to gout or kidney stones.

Zyloprim is used to treat gout or kidney stones, and to decrease levels of uric acid in people who are receiving cancer treatment.

Zyloprim may also be used for purposes not listed in this medication guide.