Hydroxyprogesterone Caproate Injection and Theraflu Cold and Sore Throat
Determining the interaction of Hydroxyprogesterone Caproate Injection and Theraflu Cold and Sore Throat and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:HYDROXYprogesterone may reduce the blood levels and effects of acetaminophen. Contact your doctor if your symptoms worsen or your condition changes during treatment with these medications. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration with hydroxyprogesterone may decrease the plasma concentrations of drugs that are metabolized by CYP450 1A2, 2A6, and/or 2B6. An in vitro study using human liver microsomes and CYP isoform-selective substrates indicated that hydroxyprogesterone caproate can increase the metabolic rate of CYP450 1A2, 2A6, and 2B6 by approximately 80%, 150%, and 80%, respectively. The clinical significance has not been determined.
MANAGEMENT: Pharmacologic effects and/or serum concentrations of the coadministered drug should be monitored more closely whenever hydroxyprogesterone is added to or withdrawn from therapy, and the dosage adjusted if an interaction is suspected.
- "Product Information. Makena (hydroxyprogesterone)." Ther-Rx Corporation, Bridgeton, MO.
Generic Name: hydroxyprogesterone
Brand name: Makena, Makena Auto-Injector, Hylutin, Delta-Lutin, Duralutin, Hyprogesterone, Prodrox
Synonyms: Hydroxyprogesterone injection, Hydroxyprogesterone Caproate
Generic Name: acetaminophen / pheniramine / phenylephrine
Brand name: Theraflu Cold and Sore Throat, Theraflu Flu and Sore Throat, Flu & Severe Cold Night Time, Theraflu Flu & Sore Throat, Theraflu Nighttime Severe Cold, Theraflu Sinus & Cold, Theraflu Cold & Sore Throat
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Hydroxyprogesterone Caproate Injection-Theraflu Cold/Cough Nighttime
- Hydroxyprogesterone Caproate Injection-Theraflu Daytime Severe Cold
- Hydroxyprogesterone Caproate Injection-Theraflu Daytime Severe Cold & Cough
- Hydroxyprogesterone Caproate Injection-Theraflu Flu & Cough
- Hydroxyprogesterone Caproate Injection-Theraflu Flu & Sore Throat
- Hydroxyprogesterone Caproate Injection-Theraflu Max-D Cold & Flu
- Theraflu Cold and Sore Throat-Hydroxyprogesterone Caproate Injection (Makena)
- Theraflu Cold and Sore Throat-Hydroxyprogesterone injection
- Theraflu Cold and Sore Throat-Hydroxyprogesterone Intramuscular
- Theraflu Cold and Sore Throat-Hydroxyquinoline vaginal
- Theraflu Cold and Sore Throat-Hydroxyurea
- Theraflu Cold and Sore Throat-Hydroxyurea Capsules 200 mg, 300 mg, 400 mg