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Hyolev MB and Sulfazine

Determining the interaction of Hyolev MB and Sulfazine and the possibility of their joint administration.

Check result:

Hyolev MB <> Sulfazine

Relevance: 08.08.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using methenamine together with sulfaSALAzine is not recommended. Combining these medications may cause crystals to form in the urine. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

CONTRAINDICATED: Some sulfonamides can form an insoluble precipitate with formaldehyde, which is generated from the hydrolysis of methenamine in acidic urine maintained by the presence of hippuric acid.

MANAGEMENT: Methenamine preparations should not be given to patients taking sulfonamides due to the risk of crystalluria. An alkalinizing agent should not be added because this may render methenamine less effective.

References

"Product Information. Urised (methenamine)." Polymedica Pharmaceuticals USA Inc, Woburn, MA.
"Product Information. Hiprex (methenamine)." Hoechst Marion-Roussel Inc, Kansas City, MO.

Hyolev MB

Generic Name: hyoscyamine / methenamine / methylene blue / phenyl salicylate / sodium biphosphate

Brand name: Azuphen MB, Hyolev MB, Phosphasal, UR N-C, Uramit MB, Urelle, Uribel, Urimar-T, Urin D/S, Uro-L, Ustell, Utira-C, Uro-MP, Vilamit MB, Vilevev MB, UR N-C, Urelle, Uretron D/S, Urin DS, Uro-458, UroAv-81, UroAv-B, Uticap, Utrona-C

Synonyms: n.a.

What is Hyolev MB?

Sulfazine

Generic Name: sulfasalazine

Brand name: Azulfidine, Azulfidine EN-tabs, Sulfazine

Synonyms: n.a.

What is Sulfazine?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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