Hyoscyamine, Atropine, Scopolamine, and Phenobarbital Elixir and Methergine (Methylergonovine Injection)
Determining the interaction of Hyoscyamine, Atropine, Scopolamine, and Phenobarbital Elixir and Methergine (Methylergonovine Injection) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:PHENobarbital may reduce the blood levels and effects of methylergonovine. Contact your doctor if your symptoms worsen or your condition changes during treatment with these medications. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration with inducers of CYP450 3A4 may decrease the plasma concentrations of ergot alkaloids, which are substrates of the isoenzyme.
MANAGEMENT: The potential for diminished therapeutic effects of ergot alkaloids should be considered when used in combination with CYP450 3A4 inducers.
- "Product Information. Methergine (methylergonovine)." Novartis Pharmaceuticals, East Hanover, NJ.
Generic Name: atropine / hyoscyamine / phenobarbital / scopolamine
Brand name: Donnatal, D-Tal, Phenohytro, Chardonna-2, Hyosophen, Donnapine, Elixiral, Bellatal, Spasmolin, Haponal, Antispas, Barbidonna, Donnatal Extentabs, Antispasmodic, Bellalphen, Donnaphen, Spasquid, Alkabel-SR, Bellatal ER, Servira, PB-Hyos, Quadrapax, Phenobarbital with Belladonna Alkaloids
Synonyms: Belladonna alkaloids and phenobarbital, Hyoscyamine, Atropine, Scopolamine, and Phenobarbital
Generic Name: methylergonovine
Brand name: Methergine
Synonyms: Methergine (oral and injection), Methergine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Hyoscyamine, Atropine, Scopolamine, and Phenobarbital Elixir-Methergine (Methylergonovine Tablets)
- Hyoscyamine, Atropine, Scopolamine, and Phenobarbital Elixir-Methergine Injection
- Hyoscyamine, Atropine, Scopolamine, and Phenobarbital Elixir-Methergine oral and injection
- Hyoscyamine, Atropine, Scopolamine, and Phenobarbital Elixir-Methimazole
- Hyoscyamine, Atropine, Scopolamine, and Phenobarbital Elixir-Methionine
- Hyoscyamine, Atropine, Scopolamine, and Phenobarbital Elixir-Methitest
- Methergine (Methylergonovine Injection)-Hyoscyamine, Atropine, Scopolamine, and Phenobarbital Tablets
- Methergine (Methylergonovine Injection)-Hyoscyamine, methenamine, methylene blue, and sodium biphosphate
- Methergine (Methylergonovine Injection)-Hyoscyamine, Methenamine, Methylene Blue, and Sodium Phosphate Monobasic
- Methergine (Methylergonovine Injection)-Hyoscyamine, methenamine, methylene blue, phenyl salicylate, and sodium phosphate
- Methergine (Methylergonovine Injection)-Hyoscyamine, methenamine, methylene blue, phenyl salicylate, sodium biphosphate
- Methergine (Methylergonovine Injection)-Hyosophen