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Ibandronate Injection and Tums Gas Relief Chewy Bites

Determining the interaction of Ibandronate Injection and Tums Gas Relief Chewy Bites and the possibility of their joint administration.

Check result:

Ibandronate Injection <> Tums Gas Relief Chewy Bites

Relevance: 07.05.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Ibandronate and calcium carbonate should not be taken orally at the same time. Products that contain magnesium, aluminum, calcium, iron, and/or other minerals may interfere with the absorption of ibandronate into the bloodstream and reduce its effectiveness. You should take calcium carbonate at least 30 minutes after the ibandronate dose. Talk to a healthcare professional if you are not sure whether a product contains something that could potentially interact with your medication or if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADJUST DOSING INTERVAL: Products containing aluminum, calcium, magnesium and other polyvalent cations such as antacids or vitamin with mineral supplements are likely to interfere with the gastrointestinal absorption of oral bisphosphonates. For example, the bioavailability of tiludronate has been shown to decrease 80% during simultaneous administration with calcium, and 60% when aluminum- or magnesium-containing antacids were administered one hour before tiludronate.

MANAGEMENT: Antacids or other oral medications containing aluminum, calcium, magnesium and other polyvalent cations should be administered at least 30 minutes after the bisphosphonate dose.

References

Darcy PF "Nutrient-drug interactions." Adverse Drug React Toxicol Rev 14 (1995): 233-54
"Product Information. Boniva (ibandronate)." Roche Laboratories, Nutley, NJ.
"Product Information. Skelid (tilundronate)." Sanofi Winthrop Pharmaceuticals, New York, NY.
"Product Information. Bonefos (clodronate)." Rhone-Poulenc Rorer Canada Inc, Laval, QC.
"Product Information. Actonel (risedronate)." Procter and Gamble Pharmaceuticals, Cincinnati, OH.
"Product Information. Fosamax (alendronate)." Merck & Co, Inc, West Point, PA.

Ibandronate Injection

Generic Name: ibandronate

Brand name: Boniva, Bondronat

Synonyms: Ibandronate (oral/injection), Ibandronate

What is Ibandronate Injection?

Tums Gas Relief Chewy Bites

Generic Name: calcium carbonate / simethicone

Brand name: Alka-Seltzer Heartburn + Gas, Gas-X with Maalox Extra Strength, Maalox Advanced Maximum Strength, Maalox Junior Plus Antigas, Tums Gas Relief Chewy Bites

Synonyms: n.a.

What is Tums Gas Relief Chewy Bites?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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