Ibandronate Injection and Vyndaqel

• Generic Name: ibandronate
• Dosage Forms: n.a.
• Other Brand Names: Boniva, Bondronat

• It is used to treat soft, brittle bones (osteoporosis) in women after change of life.
• It is used to put off soft, brittle bones (osteoporosis) in women after change of life.
• It may be given to you for other reasons. Talk with the doctor.

• Generic Name: tafamidis
• Dosage Forms: capsule, liquid filled
• Other Brand Names: Vyndamax, Vyndaqel

Vyndaqel affects a protein called transthyretin (TTR, made primarily in the liver). Transthyretin-mediated amyloidosis (ATTR) is a condition in which abnormal deposits of TTR protein build-up in many parts of the body, interfering with normal function. A build-up of TTR in the heart can lead to heart failure.

People with hereditary ATTR amyloidosis have a DNA mutation that can be passed from one generation to the next. People with wild-type ATTR amyloidosis do not have abnormal DNA and cannot pass on the condition.

Vyndaqel is used in adults with hereditary or wild type ATTR to treat cardiomyopathy (damage of the heart muscle) caused by a build-up of TTR.

Vyndaqel may also be used for purposes not listed in this medication guide.