Ibuprofen and pseudoephedrine and Retrovir Infusion
Determining the interaction of Ibuprofen and pseudoephedrine and Retrovir Infusion and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using zidovudine together with ibuprofen may increase the risk of bleeding in HIV-positive patients with hemophilia. However, the interaction is not fully understood, and evidence is limited. Talk to your doctor or pharmacist if you have any concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Limited clinical data suggest that the concomitant use of zidovudine with nonsteroidal anti-inflammatory agents may increase the risk of hematological toxicity and/or bleeding in HIV-positive patients with hemophilia. The mechanism is unknown.
MANAGEMENT: It is recommended to monitor patients for side effects and bleeding during concomitant use.
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- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
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- Sahai J, Gallicano K, Conway B, et al. "Lack of pharmacokinetic interaction between naproxen (N) and zidovudine (Z)." Clin Pharmacol Ther 51 (1992): 184
- Sahai J, Gallicano K, Garber G, et al. "Evaluation of the in vivo effect of naproxen on zidovudine pharmacokinetics in patients infected with human immunodeficiency virus." Clin Pharmacol Ther 52 (1992): 464-70
- Burger DM, Meenhorst PL, Koks CH, Beijnen JH "Drug interactions with zidovudine." AIDS 7 (1993): 445-60
Generic Name: ibuprofen / pseudoephedrine
Brand name: Advil Cold & Sinus, Advil Cold and Sinus Liqui-Gel, Dimetapp Sinus, Dristan Sinus, Motrin IB Sinus, Sine-Aid IB, Dayquil Pressure and Pain Caplet, Motrin Cold and Flu, Motrin Childrens Cold, Motrin Sinus Headache, Dimetapp Childrens Cold & Fever, Children's Ibuprofen Cold Relief
Synonyms: n.a.
Generic Name: zidovudine
Brand name: Retrovir
Synonyms: Zidovudine (oral/injection), Zidovudine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Ibuprofen and pseudoephedrine-Retrovir Intravenous
- Ibuprofen and pseudoephedrine-Retrovir oral/injection
- Ibuprofen and pseudoephedrine-Revatio
- Ibuprofen and pseudoephedrine-Revatio Injection
- Ibuprofen and pseudoephedrine-Revatio Intravenous
- Ibuprofen and pseudoephedrine-Revefenacin
- Retrovir Infusion-Ibuprofen Capsules
- Retrovir Infusion-Ibuprofen Chewable Tablets
- Retrovir Infusion-Ibuprofen Immediate Release Tablets
- Retrovir Infusion-Ibuprofen injection
- Retrovir Infusion-Ibuprofen Injection (PDA)
- Retrovir Infusion-Ibuprofen Intravenous