Ibuprofen and pseudoephedrine and Ticlopidine
Determining the interaction of Ibuprofen and pseudoephedrine and Ticlopidine and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using ibuprofen together with ticlopidine can cause you to bleed more easily. Call your doctor promptly if you have any unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness. You should also avoid any other over-the-counter NSAID products. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Ticlopidine has been reported to potentiate the effect of nonsteroidal anti-inflammatory agents (NSAIDs) on platelet aggregation. The risk of bleeding may be increased, especially in patients with a history of gastrointestinal (GI) ulceration or bleeding. The safety of concomitant use has not been established.
MANAGEMENT: Patients should be monitored for signs and symptoms of bleeding, especially GI bleeding, if NSAIDs and ticlopidine are coadministered. They should be advised to promptly report any signs of bleeding to their physician, including abdominal pain, vomiting blood, red or black stools, swelling, headache, dizziness, weakness, prolonged bleeding from cuts, nosebleeds, bleeding of gums from brushing, red or brown urine, or other unusual bleeding or bruising. Patients should also be counseled to avoid any other over-the-counter NSAID products.
- "Product Information. Ticlid (ticlopidine)." Syntex Laboratories Inc, Palo Alto, CA.
Generic Name: ibuprofen / pseudoephedrine
Brand name: Advil Cold & Sinus, Advil Cold and Sinus Liqui-Gel, Dimetapp Sinus, Dristan Sinus, Motrin IB Sinus, Sine-Aid IB, Dayquil Pressure and Pain Caplet, Motrin Cold and Flu, Motrin Childrens Cold, Motrin Sinus Headache, Dimetapp Childrens Cold & Fever, Children's Ibuprofen Cold Relief
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Ibuprofen and pseudoephedrine-Ticlopidine Hydrochloride
- Ibuprofen and pseudoephedrine-Ticon
- Ibuprofen and pseudoephedrine-Ticon oral/injection
- Ibuprofen and pseudoephedrine-Tigan
- Ibuprofen and pseudoephedrine-Tigan (Trimethobenzamide Capsules)
- Ibuprofen and pseudoephedrine-Tigan (Trimethobenzamide Injection Solution)
- Ticlopidine-Ibuprofen Capsules
- Ticlopidine-Ibuprofen Chewable Tablets
- Ticlopidine-Ibuprofen Immediate Release Tablets
- Ticlopidine-Ibuprofen injection
- Ticlopidine-Ibuprofen Injection (PDA)
- Ticlopidine-Ibuprofen Intravenous