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Ibutilide Fumarate Injection and Quinidex Extentabs

Determining the interaction of Ibutilide Fumarate Injection and Quinidex Extentabs and the possibility of their joint administration.

Check result:
Ibutilide Fumarate Injection <> Quinidex Extentabs
Relevance: 16.06.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using quiNIDine and ibutilide is not recommended. Taking these drugs together can cause pain or discomfort in your chest, shortness of breath, unusual heartbeats, or feeling dizzy or lightheaded. . It is important that you tell your healthcare provider about all other medications that you are using including vitamins and herbs. Do not stop using your medications without talking to your doctor first.

Professional:

CONTRAINDICATED: Class I antiarrhythmic agents and ibutilide have additive effects and may potentially prolong cardiac refractoriness.

MANAGEMENT: Class I antiarrhythmic agents should not be given concomitantly with ibutilide or within four hours after ibutilide is given. In clinical trials, other class I agents were withheld for at least five half-lives prior to ibutilide infusion and for four hours after dosing, but thereafter were allowed at the physician's discretion.

References
  • "Product Information. Corvert (ibutilide)." Pharmacia and Upjohn, Kalamazoo, MI.
Ibutilide Fumarate Injection

Generic Name: ibutilide

Brand name: Corvert

Synonyms: Ibutilide

Quinidex Extentabs

Generic Name: quinidine

Brand name: Quin-G, Cardioquin, Quinora, Quinidex Extentabs, Quinaglute Dura-Tabs, Quin-Release

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.