Ibutilide Fumarate Injection and Ranitidine Hydrochloride

• Generic Name: ibutilide
• Dosage Forms: injection, solution
• Other Brand Names: Corvert

Ibutilide is an anti-arrhythmic heart medication that corrects certain conditions of irregular heart rhythm.

Ibutilide is used to help keep the heart beating normally in people with certain heart rhythm disorders of the atrium (the upper chambers of the heart that allow blood to flow into the heart). Ibutilide is used in people with atrial fibrillation or atrial flutter.

Ibutilide may also be used for purposes not listed in this medication guide.

• Generic Name: ranitidine
• Dosage Forms: n.a.
• Other Brand Names: Zantac

Short-term treatment of active duodenal ulcer (endoscopically or radiographically confirmed).

Maintenance of healing and reduction in recurrence of duodenal ulcer.

Long-term treatment of Zollinger-Ellison syndrome, systemic mastocytosis, postoperative hypersecretion, “short-gut” syndrome.

Short-term treatment of active benign gastric ulcer.

Maintenance of healing and reduction in recurrence of gastric ulcer.

Treatment of GERD to achieve acid suppression, control symptoms, and prevent complications.

Treatment of erosive esophagitis (endoscopically diagnosed) in patients with GERD.

Maintain healing and decrease recurrence of erosive esophagitis.

Self-medication as initial therapy for less severe symptomatic GERD.

Short-term self-medication for treatment of heartburn (pyrosis) symptoms associated with acid indigestion and sour stomach in adults and adolescents ≥12 years of age.

Short-term self-medication for prevention of heartburn symptoms associated with acid indigestion and sour stomach brought on by ingestion of certain foods and beverages in adults and children ≥12 years of age.

May be useful for increasing gastric pH in neonates (<1 month of age) at risk for GI hemorrhage during ECMO.