About us Contacts Drug interactions: 390 212
Drug search by name

Ifosfamide and NegGram

Determining the interaction of Ifosfamide and NegGram and the possibility of their joint administration.

Check result:
Ifosfamide <> NegGram
Relevance: 05.06.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using nalidixic acid and ifosfamide is not recommended. Taking these drugs together can cause symptoms of easy bruising or bleeding, unusual weakness, nausea, stomach pain, low fever, or loss of appetite. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

CONTRAINDICATED: Serious gastrointestinal toxicity such as hemorrhagic ulcerative colitis and intestinal necrosis has been reported with the concomitant use of nalidixic acid and melphalan. The mechanism of interaction has not been described.

MANAGEMENT: The concomitant use of nalidixic acid in patients undergoing therapy with melphalan or other related cancer chemotherapeutic alkylating agents is considered contraindicated.

References
  • "Product Information. NegGram (nalidixic acid)." Sanofi Winthrop Pharmaceuticals, New York, NY.
Ifosfamide

Generic Name: ifosfamide

Brand name: Ifex

Synonyms: n.a.

NegGram

Generic Name: nalidixic acid

Brand name:

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction