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Ifosfamide and Mesna Injection and Oprelvekin

Determining the interaction of Ifosfamide and Mesna Injection and Oprelvekin and the possibility of their joint administration.

Check result:
Ifosfamide and Mesna Injection <> Oprelvekin
Relevance: 19.03.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using ifosfamide together with oprelvekin can cause abnormally low potassium concentration in the blood. You may need a dose adjustment in addition to special testing of your blood. Call your doctor promptly if you have any symptoms of shortness of breath, swelling, uneven heartbeats, and chest pain. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR CLOSELY: The manufacturer of oprelvekin warns that sudden deaths have occurred in patients receiving oprelvekin, ifosfamide, and chronic diuretic therapy who developed hypokalemia (3 mEq/mL or less).

MANAGEMENT: Close clinical and laboratory monitoring of fluid and electrolyte status is recommended if this combination must be given to patients receiving diuretics.

References
  • "Product Information. Neumega (oprelvekin)." Genetics Institute, Cambridge, MA.
Ifosfamide and Mesna Injection

Generic Name: ifosfamide / mesna

Brand name:

Synonyms: n.a.

Oprelvekin

Generic Name: oprelvekin

Brand name:

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle