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Iloprost inhalation and Medicidin-D

Determining the interaction of Iloprost inhalation and Medicidin-D and the possibility of their joint administration.

Check result:
Iloprost inhalation <> Medicidin-D
Relevance: 03.11.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Ask your doctor before using phenylephrine together with iloprost. Using these medications together can make iloprost less effective. You should be counseled to consult with your doctor before taking over-the-counter decongestants. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Concurrent administration of decongestants or vasoconstrictors may negate the vasodilatory effects of prostacyclin analogs in patients with pulmonary hypertension.

MANAGEMENT: The use of decongestants and vasoconstrictors should probably be avoided in patients with pulmonary hypertension. Patients should be counseled to consult with their physician before taking over-the-counter decongestants such as phenylephrine and pseudoephedrine.

References
  • Hardman JG, Gilman AG, Limbird LE eds. "Goodman and Gilman's the Pharmacological Basis of Therapeutics. 9th ed." New York, NY: McGraw-Hill (1995):
  • "Product Information. Remodulin (treprostinil)." United Therapeutics Corp, Silver Spring, MD.
  • "Product Information. Flolan (epoprostenol)." Glaxo Wellcome, Research Triangle Park, NC.
Iloprost inhalation

Generic Name: iloprost

Brand name: Ventavis

Synonyms: Iloprost

Medicidin-D

Generic Name: acetaminophen / chlorpheniramine / phenylephrine

Brand name: Allergy Multi-Symptom, Allergy Multi-Symptom Daytime, Comtrex Flu Therapy Day/Night, Comtrex Severe Cold & Sinus, Contac Cold+Flu Maximum Strength, Gendecon, Protid, Dryphen, Comtrex Flu Therapy, Sinus Congestion & Pain Nighttime, Allergy Relief Multi-Symptom, Tylenol Sinus Congestion-Pain Cool Burst, Relief-PE, Contact Cold and Flu Night, Cold Relief Plus, EQL Effervescent Plus Cold, GNP Cold Relief Plus, QC Cold Relief Plus

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction