Imipramine Hydrochloride and Measles, mumps, rubella and varicella (MMRV) vaccine

• Generic Name: imipramine
• Dosage Forms: n.a.
• Other Brand Names: Tofranil, Tofranil-PM

Management of major depressive disorder.

Results of several studies of TCAs in preadolescent and adolescent patients with major depression indicate lack of overall efficacy in this age group.

Temporary adjunctive therapy in the treatment of nocturnal enuresis (bed-wetting) in children ≥6 years of age.

Safety and efficacy of long-term use not established.

Management of panic disorder with or without agoraphobia.

Second-line agent in attention deficit hyperactivity disorder (ADHD) in patients unable to tolerate or unresponsive to stimulants.

Associated with a narrower margin of safety than some other therapeutic agents; use only if clearly indicated and with careful monitoring, including baseline and subsequent determinations of ECG and other parameters.

Has been used for management of eating disorders (e.g., bulimia, anorexia nervosa) with equivocal results; avoid use in underweight individuals and in those exhibiting suicidal ideation.

Has been used for the short-term management of acute depressive episodes in bipolar disorder.

TCAs associated with a greater risk of precipitating hypomania or manic episodes than other classes of antidepressants; should always be used in combination with a mood stabilizer (e.g., lithium).

Has been used for the management of acute depressive episodes (in combination with an antipsychotic) in patients with schizophrenia.

Has been used for the management of anxiety (in combination with an anxiolytic, a sedative, or an antipsychotic) in patients with depression.

Among the drugs of choice for the symptomatic treatment of postherpetic neuralgia.

Less effective for insomnia and associated with more serious adverse reactions than conventional hypnotics.

• Generic Name: measles virus vaccine / mumps virus vaccine / rubella virus vaccine / varicella virus vaccine
• Dosage Forms: n.a.
• Other Brand Names: ProQuad

Measles, mumps, rubella, and varicella are serious diseases caused by viruses spread from person to person through the air or by skin to skin contact.

Measles, mumps, rubella, and varicella can cause minor symptoms such as fever, tiredness, headache, sore throat, cough, swollen glands, runny nose, eye irritation, skin rash, muscle aches, and joint pain.

More serious symptoms of measles or mumps include pneumonia, hearing loss, painful swelling of the testicles or ovaries, and rarely permanent brain damage or death.

Becoming infected with rubella virus (also called German Measles) during pregnancy can result in a miscarriage or serious birth defects.

Varicella (chickenpox) can also cause a breakout of fluid-filled blisters on the skin. Chickenpox is usually mild, but it can lead to severe skin infection, breathing problems, brain damage, or death. A person who has had chickenpox can develop herpes zoster (also called shingles) later in life, which causes severe nerve pain, and hearing or vision problems, which may last for months or years.

The measles, mumps, rubella, and varicella (MMRV) vaccine is used to help prevent these diseases in children. This vaccine causes your body to develop immunity to the disease. This vaccine will not treat an active infection that has already developed in the body.

MMRV vaccine is for use in children between the ages of 12 months and 12 years old.

Like any vaccine, the MMRV vaccine may not provide protection from disease in every person.