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Incobotulinumtoxina Intramuscular and Lorzone

Determining the interaction of Incobotulinumtoxina Intramuscular and Lorzone and the possibility of their joint administration.

Check result:

Incobotulinumtoxina Intramuscular <> Lorzone

Relevance: 01.09.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using chlorzoxazone before or after incobotulinumtoxinA may increase the severity of muscle weakness you may experience from treatment with incobotulinumtoxinA. Let your doctor know if you develop excessive muscle weakness. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Excessive muscle weakness associated with the use of botulism toxin may be exaggerated by concomitant use of a skeletal muscle relaxant. Botulinum toxin inhibits the release of acetylcholine from peripheral cholinergic nerve endings and is a neuromuscular blocking agent, thus additive effects may occur with muscle relaxants.

MANAGEMENT: Patients should be advised that muscle weakness may be increased when botulinum toxin is used in combination with skeletal muscle relaxants.

References

"Product Information. Dysport (abobotulinumtoxinA)." Tercica Inc, Brisbane, CA.
"Product Information. Xeomin (botulinum toxin type A (obsolete) (botulinum toxin type A))." Merz Pharmaceuticals, Greensboro, NC.
"Product Information. Myobloc (botulinum toxin type B)" Elan Pharmaceuticals, S. San Francisco, CA.
"Product Information. Botox (onabotulinumtoxin A)." Allergan Inc, Irvine, CA.

Incobotulinumtoxina Intramuscular

Generic Name: incobotulinumtoxinA

Brand name: Xeomin

Synonyms: Incobotulinumtoxina (Intramuscular)

What is Incobotulinumtoxina Intramuscular?

Lorzone

Generic Name: chlorzoxazone

Brand name: Lorzone, Paraflex, Remular-S, Parafon Forte DSC, Relaxazone, Eze DS, Remular, Strifon Fort

Synonyms: Lorzone Tablets

What is Lorzone?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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