Incruse Ellipta and Lorlatinib

• Generic Name: umeclidinium
• Dosage Forms: aerosol, powder
• Other Brand Names: Incruse Ellipta

Incruse Ellipta (umeclidinium) is an anticholinergic that works by relaxing muscles in the airways to improve breathing.

Incruse Ellipta is used to prevent airflow obstruction and reduce flare-ups in adults with COPD (chronic obstructive pulmonary disease, including bronchitis and emphysema.

Incruse Ellipta is for use only in people with COPD and should not be used to treat asthma.

• Generic Name: lorlatinib
• Dosage Forms: n.a.
• Other Brand Names: Lorbrena

Lorlatinib is used to treat a certain type of non-small cell lung cancer that has spread to other parts of the body.

Lorlatinib is used only if your cancer has a specific genetic marker (an abnormal "ALK" gene). Your doctor will test you for this gene.

Lorlatinib is given after other cancer treatments did not work or have stopped working.

Lorlatinib was approved by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, some people responded to lorlatinib, but further studies are needed.

Lorlatinib may also be used for purposes not listed in this medication guide.