Inderal and Mefloquine

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using propranolol together with mefloquine can affect the rhythm of your heart. Call your doctor if you have symptoms of irregular heartbeat, chest tightness, blurred vision or nausea. You may need a dose adjustment or special test if you take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Coadministration of mefloquine and propranolol may increase the risk of bradycardia. Cardiopulmonary arrest has been reported after a single dose of mefloquine in a patient taking propranolol. The mechanism is unknown and causality is unclear. Mefloquine monotherapy or combination therapy with other drugs that affect cardiac conduction may cause ECG changes.

MANAGEMENT: Clinical monitoring is advisable for patients receiving this combination. The potential risk to patients with heart disease should be weighed against the expected benefits of mefloquine treatment.

Inderal

Generic Name: propranolol

Brand name: Inderal LA, Inderal XL, InnoPran XL, Inderal, Hemangeol, InnoPran XL

Synonyms: n.a.

What is Inderal?

Mefloquine

Generic Name: mefloquine

Brand name: Lariam

Synonyms: n.a.

What is Mefloquine?