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Inderal and Relpax

Determining the interaction of Inderal and Relpax and the possibility of their joint administration.

Check result:
Inderal <> Relpax
Relevance: 15.06.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Coadministration with propranolol has been shown to increase the peak plasma concentration (Cmax) and area under the concentration-time curve (AUC) of eletriptan by 10% and 33%, respectively. The mechanism of interaction is unknown. No interactive increases in blood pressure were observed during the combination, and no dosage adjustment appears to be necessary.

References
  • "Product Information. Relpax (eletriptan)." Pfizer U.S. Pharmaceuticals, New York, NY.
Inderal

Generic Name: propranolol

Brand name: Inderal LA, Inderal XL, InnoPran XL, Inderal, Hemangeol, InnoPran XL

Synonyms: n.a.

Relpax

Generic Name: eletriptan

Brand name: Relpax

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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