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Inderal and Rimactane

Determining the interaction of Inderal and Rimactane and the possibility of their joint administration.

Check result:

Inderal <> Rimactane

Relevance: 15.06.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using propranolol together with rifAMPin can decrease the effects of propranolol. Contact your doctor if your condition worsens or if you have an increase in blood pressure. You may need a dose adjustment or need your blood pressure checked more often. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Rifampin may decrease serum levels and effects of some oral beta-blockers. The proposed mechanism is increased CYP450 oxidative metabolism of beta-blockers that are hepatically metabolized. Renally excreted beta-blockers such as atenolol, carteolol, nadolol, or sotalol are not expected to interact.

MANAGEMENT: Patients should be monitored for clinical response and tolerance when rifampin is added to or discontinued from a beta-blocker regimen. The beta-blocker dosage may require adjustment.

References

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"Product Information. Cartrol (carteolol)." Abbott Pharmaceutical, Abbott Park, IL.
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Inderal

Generic Name: propranolol

Brand name: Inderal LA, Inderal XL, InnoPran XL, Inderal, Hemangeol, InnoPran XL

Synonyms: n.a.

What is Inderal?

Rimactane

Generic Name: rifampin

Brand name: Rifadin, Rifadin IV, Rimactane

Synonyms: n.a.

What is Rimactane?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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