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Inderal and Velcade

Determining the interaction of Inderal and Velcade and the possibility of their joint administration.

Check result:
Inderal <> Velcade
Relevance: 15.06.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Coadministration with bortezomib may increase the plasma concentrations of drugs that are substrates of the CYP450 2C19 isoenzyme. The clinical significance is unknown, as bortezomib is considered a weak inhibitor of CYP450 2C19 in vitro.

References
  • "Product Information. Velcade (bortezomib)." Millennium Pharmaceuticals Inc, Cambridge, MA.
Inderal

Generic Name: propranolol

Brand name: Inderal LA, Inderal XL, InnoPran XL, Inderal, Hemangeol, InnoPran XL

Synonyms: n.a.

Velcade

Generic Name: bortezomib

Brand name: Velcade

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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