Indocin and Niraparib Tosylate

• Generic Name: indomethacin
• Dosage Forms: rectal suppository
• Other Brand Names: Indocin, Indocin SR, Tivorbex

Indocin is a nonsteroidal anti-inflammatory drug (NSAID).

Indocin is used to treat moderate to severe osteoarthritis, rheumatoid arthritis, gouty arthritis, or ankylosing spondylitis. This medicine is also used to treat shoulder pain caused by bursitis or tendinitis.

Extended-release Indocin (Indocin SR) should not be used to treat gouty arthritis.

Indocin may also be used for purposes not listed in this medication guide.

• Generic Name: niraparib
• Dosage Forms: n.a.
• Other Brand Names: Zejula

Maintenance therapy of recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer in patients in complete or partial response following platinum-based chemotherapy (designated an orphan drug by FDA for this use).

In the principal efficacy study (NOVA), niraparib maintenance therapy substantially prolonged progression-free survival in patients with platinum-sensitive epithelial ovarian, fallopian tube, or primary peritoneal cancer compared with placebo regardless of the presence or absence of germline BRCA mutations or homologous recombination deficiency (HRD) status.