Indoor/Outdoor Allergy Relief and Theophylline and guaifenesin

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Coadministration with theophylline may decrease the clearance of cetirizine. The mechanism of interaction is unknown. According to the product labeling, a small decrease in the clearance of cetirizine was observed when given with a 400 mg dose of theophylline, and it is possible that larger theophylline doses could have a greater effect. No clinically significant drug interaction has been found with theophylline at a low dose. Steady-state cetirizine (10 mg twice daily for 3.5 days) has also been found to have no significant effects on the pharmacokinetics of theophylline (240 mg intravenously one hour after the last dose of cetirizine) in six healthy volunteers compared to placebo, and vice versa.

Indoor/Outdoor Allergy Relief

Generic Name: cetirizine

Brand name: Zyrtec, All Day Allergy, All Day Allergy Children's, Indoor/Outdoor Allergy Relief, Zyrtec, GoodSense All Day Allergy

Synonyms: Cetirizine, Cetirizine (Systemic)

What is Indoor/Outdoor Allergy Relief?

Theophylline and guaifenesin

Generic Name: guaifenesin / theophylline

Brand name:

Synonyms: Theophylline and guaifenesin (Oral)

What is Theophylline and guaifenesin?