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Infumorph and Yohimbe

Determining the interaction of Infumorph and Yohimbe and the possibility of their joint administration.

Check result:

Infumorph <> Yohimbe

Relevance: 17.05.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

A double-blind, placebo-controlled study of patients with postoperative dental pain found that while yohimbine itself did not affect pain, the overall analgesic effect of morphine was significantly enhanced in the presence of yohimbine. The mechanism of interaction is unknown. Additional research involving other pain states is needed.

References

Gear RW, Gordon NC, Heller PH, Levine JD "Enhancement of morphine analgesia by the alpha(2)-adrenergic antagonist yohimbine." Neuroscience 66 (1995): 5-8

Infumorph

Generic Name: morphine

Brand name: Duramorph PF, Infumorph, Mitigo, Arymo ER, Kadian, MorphaBond ER, Avinza, MS Contin, RMS, Roxanol

Synonyms: Infumorph (injection)

What is Infumorph?

Yohimbe

Generic Name: yohimbine

Brand name:

Synonyms: n.a.

What is Yohimbe?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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