InnoPran XL and Levothyroxine Tablets
Determining the interaction of InnoPran XL and Levothyroxine Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Thyroid hormone therapy may reverse decreased hepatic blood flow associated with hypothyroidism. Increased hepatic metabolism and decreased serum levels of some beta-blockers may result. Data are available for propranolol only. No special precautions are necessary. When hypothyroidism is converted to a euthyroid state, a decrease in beta-blocking effectiveness is possible.
- Aro A, Antila M, Korhonen T, Sundquist H "Pharmacokinetics of propranolol and sotalol in hyperthyroidism." Eur J Clin Pharmacol 21 (1982): 373-7
- Wells PG, Feely J, Wilkinson GR, Wood AJ "Effect of thyrotoxicosis on liver blood flow and propranolol disposition after long-term dosing." Clin Pharmacol Ther 33 (1983): 603-8
Generic Name: propranolol
Brand name: Hemangeol, Inderal LA, Inderal XL, InnoPran XL, Inderal, InnoPran XL
Synonyms: n.a.
Generic Name: levothyroxine
Brand name: Levoxyl, Synthroid, Tirosint, Unithroid, Euthyrox, Levothroid, Tirosint-Sol
Synonyms: Levothyroxine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- InnoPran XL-Levoxyl
- InnoPran XL-Levsin
- InnoPran XL-Levsin (Hyoscyamine Injection)
- InnoPran XL-Levsin (Hyoscyamine Tablets)
- InnoPran XL-Levsin Tablets
- InnoPran XL-Levsin/SL
- Levothyroxine Tablets-Inomax
- Levothyroxine Tablets-INOmax inhalation gas
- Levothyroxine Tablets-Inotersen
- Levothyroxine Tablets-Inotersen Sodium
- Levothyroxine Tablets-Inotersen Subcutaneous
- Levothyroxine Tablets-Inotuzumab ozogamicin