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InnoPran XL and Parcopa

Determining the interaction of InnoPran XL and Parcopa and the possibility of their joint administration.

Check result:

InnoPran XL <> Parcopa

Relevance: 11.01.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Levodopa and propranolol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: The hypotensive effects of levodopa and antihypertensive agents may be additive. Postural hypotension may occur.

MANAGEMENT: Hemodynamic responses should be monitored during coadministration, especially during the first few weeks of therapy. Dose adjustments of the antihypertensive agent may be required. Patients should be advised to notify their physician if they experience dizziness or syncope.

References

"Product Information. Stalevo 150 (carbidopa/entacapone/levodopa)." Novartis Pharmaceuticals, East Hanover, NJ.

InnoPran XL

Generic Name: propranolol

Brand name: Hemangeol, Inderal LA, Inderal XL, InnoPran XL, Inderal, InnoPran XL

Synonyms: n.a.

What is InnoPran XL?

Parcopa

Generic Name: carbidopa / levodopa

Brand name: Parcopa, Rytary, Sinemet, Sinemet CR, Duopa

Synonyms: n.a.

What is Parcopa?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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