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InnoPran XL and Zyflo CR

Determining the interaction of InnoPran XL and Zyflo CR and the possibility of their joint administration.

Check result:

InnoPran XL <> Zyflo CR

Relevance: 11.01.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using propranolol together with zileuton may increase the effects of propranolol. Contact your doctor if you experience uneven heartbeats, shortness of breath, bluish-colored fingernails, dizziness, weakness, fainting, or seizure (convulsions). If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Zileuton is believed to inhibit the hepatic metabolism of propranolol. Propranolol serum concentrations may increase by as much as 100% with a resultant increase in beta blockade.

MANAGEMENT: If zileuton and propranolol must be given concomitantly, the patient should be observed closely for altered propranolol effects and the dose adjusted accordingly. Patients should be advised to notify their physician if they experience syncope,slow pulse, irregular heartbeat, dizziness, or shortness of breath.

References

"Product Information. Zylo Filmtab (zileuton)." Abbott Pharmaceutical, Abbott Park, IL.

InnoPran XL

Generic Name: propranolol

Brand name: Hemangeol, Inderal LA, Inderal XL, InnoPran XL, Inderal, InnoPran XL

Synonyms: n.a.

What is InnoPran XL?

Zyflo CR

Generic Name: zileuton

Brand name: Zyflo, Zyflo CR

Synonyms: n.a.

What is Zyflo CR?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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