Inspra and Phenylephrine, Carbetapentane, Potassium Guaiacolsulfonate

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using eplerenone together with potassium guaiacolsulfonate is not recommended. Combining these medications may significantly increase potassium levels in the blood. High levels of potassium can develop into a condition known as hyperkalemia, which in severe cases can lead to kidney failure, muscle paralysis, irregular heart rhythm, and cardiac arrest. You may be more likely to develop hyperkalemia while using eplerenone or potassium guaiacolsulfonate if you are elderly, dehydrated, or have kidney disease, diabetes, or advanced heart failure. Regular or long-term use of nonsteroidal anti-inflammatory drugs such as ibuprofen or naproxen (Aleve) may also increase your risk. It is important that you maintain adequate fluid intake during treatment with these medications. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat, as these may be symptoms of hyperkalemia. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

CONTRAINDICATED: The principal risk of eplerenone is hyperkalemia. Coadministration with potassium salts or potassium-sparing diuretics may increase this risk due to additive pharmacodynamic effects.

MANAGEMENT: Given the potential for serious, sometimes fatal cardiac arrhythmias associated with hyperkalemia, the use of eplerenone with potassium salts or potassium-sparing diuretics is considered contraindicated.

Inspra

Generic Name: eplerenone

Brand name: Inspra

Synonyms: n.a.

What is Inspra?

Phenylephrine, Carbetapentane, Potassium Guaiacolsulfonate

Generic Name: carbetapentane / phenylephrine / potassium guaiacolsulfonate

Brand name:

Synonyms: n.a.

What is Phenylephrine, Carbetapentane, Potassium Guaiacolsulfonate?